Fadel, AbdulmannanPlunkett, AndrewLi, WeiliAshworth, Jason J.2018-03-142018-03-142017-11-30Fadel, A., Plunkett, A., Li, W., & Ashworth, J. J. (2017). Modulation of Innate and Adaptive Immune Responses by Arabinoxylans. Journal of Food Biochemistry, 42(2), e12473. http://doi.org/10.1111/jfbc.1247310.1111/jfbc.12473http://hdl.handle.net/10034/620940This is the peer reviewed version of the following article: Fadel, A., Plunkett, A., Li, W., & Ashworth, J. J. (2017). Modulation of Innate and Adaptive Immune Responses by Arabinoxylans. Journal of Food Biochemistry, 42(2), e12473. http://doi.org/10.1111/jfbc.12473, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/jfbc.12473/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-ArchivingHumans are exposed to harmful pathogens and a wide range of noxious substances every day.The immune system reacts to, and destroys, these pathogens and harmful substances. The immunesystem is composed of innate and adaptive immunity, which liaise to protect the host and maintainhealth. Foods, especially cereals, have been reported to modulate the immune response.Arabinoxylans are nonstarch polysaccharides that have been shown to possess immune-modulatory activities. This review article discusses the fundamentals of the immune system andprovides an overview of the immunomodulatory potential of arabinoxylans in conjunction withtheir structural characteristics and proposed similarities with lipopolysaccharidesenhttp://creativecommons.org/licenses/by-nc/4.0/Adaptive immunityArabinoxylansInnate immunityLipopolysaccharidesNitric oxideArticle1745-4514Journal of Food Biochemistry