Audain, Keiron A.Zotor, Francis B.Amuna, PaulEllahi, Basma2015-03-302015-03-302015-03-12Audain, K. A., Zotor, F. B., Amuna, P., & Ellahi, B. (2015). Food supplementation among HIV-infected adults in Sub-Saharan Africa: Impact on treatment adherence and weight gain. Proceedings of the Nutrition Society, 74(04), 517-525. doi: 10.1017/S00296651150000630029-665110.1017/S0029665115000063http://hdl.handle.net/10034/347307This is the author's manuscript of an article published in the Proceedings of the Nutrition Society.Sub-Saharan Africa has the highest proportion of undernourished people in the world, along with the highest number of people living with HIV and AIDS. Thus, as a result of high levels of food insecurity many HIV patients are also undernourished. The synergism between HIV and undernutrition leads to poor treatment adherence and high mortality rates. Undernutrition has a debilitating effect on the immune system due to key nutrient deficiencies and the overproduction of reactive species (oxidative stress), which causes rapid HIV progression and the onset of AIDS. Therapeutic food supplementation used in the treatment of severe acute malnutrition is being applied to HIV palliative care; however, little biochemical data exist to highlight its impact on oxidative stress and immune recovery.enArchived with thanks to Proceedings of the Nutrition Societyoxidative stressmalnutritionHIVAIDStherapeutic foodfood multi-mix conceptArticle1475-2719Proceedings of the Nutrition Society