Ersoy, UfukAlameddine, MoussiraKanakis, IoannisStaunton, Caroline AmyPeffers, Mandy J.Jackson, Malcolm J.Goljanek-Whysall, KatarzynaVasilaki, Aphrodite2023-08-212023-08-212023-08-11Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C.A., Peffers, M.J., Jackson, M.J., Goljanek-Whysall, K., & Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In L. Saso, A. Giuffrè, G. Valacchi, & M. Maccarrone (Eds.), Modulation of Oxidative Stress (pp. 71-80). Academic Press.978044319247010.1016/B978-0-443-19247-0.00002-3http://hdl.handle.net/10034/627992This book chapter is not available on ChesterRepReactive oxygen species (ROS) serve as signaling molecules in the regulation of biological and physiological processes. Fluctuations in ROS levels play a crucial role in cellular function, proliferation, differentiation, and apoptosis during embryonic development. There is a strong association between early-life suboptimal growth and enhanced risk of development of chronic disorders in later life. This chapter aims to discuss the effects of maternal nutrition on redox homeostasis of the offspring at different stages of their life as a potential underlying mechanism in mediating the effects of early-life nutrition on the development of diseases in later life.Age-related diseasesMaternal nutritionMitochondrial dysfunctionOxidative stressRedox homeostasisBook chapter