Fallows, StephenWarren, JemOyelami, Abiola I.2023-03-152023-03-152022-06Oyelami, A. I. (2022). Medication adherence among patients with heart failure in Nigeria: From the patients’ and healthcare professionals’ perspectives [Unpublished doctoral thesis]. University of Chester.http://hdl.handle.net/10034/627662Introduction Although the efficacious pharmacotherapy advancements in the treatment of Heart Failure (HF) have been widely documented, mortality rates and hospitalisation rates among patients with HF remain high. An important reason for recurrent hospitalisation is patients’ nonadherence to self-care recommendations. Globally, medication nonadherence is a public health concern and a common phenomenon amongst patients with HF. This represents a continuous burden for patients, their relatives and the health-care system. The overall aim of this research is to develop an in-depth understanding of the issue of medication adherence among patients with HF in Nigeria by integrating the perspectives of both the patients and the healthcare providers. Methods Firstly, a review of empirical literature/qualitative meta-synthesis was conducted to explore the facilitators and barriers to adherence in heart failure. Secondly, a qualitative method by the means of in-depth, semi-structured interviews was utilised in exploring the perspectives of the patients, alongside their caregivers and their healthcare professionals regarding the factors they perceive are barriers and facilitators of medication adherence. The lived experience of patients living with HF was also explored. The results of which are discussed in two chapters. By the means of purposive sampling, a total of 65 participants (45 patients alongside their caregivers and 20 healthcare professionals) who met the inclusion criteria participated in this study. The interviews were recorded, transcribed verbatim and analysed by thematic content analysis. Results The rate of medication adherence was suboptimal (33%). The main barriers identified by the patients and their healthcare professionals include financial constraints, influence of religious beliefs, and culture, patients’ attitude and behaviour towards their medications, knowledge deficit, forgetfulness, interaction with the healthcare system among others. Experiencing side effects was a barrier identified by the patients but not the healthcare professionals. The key facilitators of medication adherence identified were forming a routine, support from family and friends, health education and counselling, and insight about the condition, medications prescribed and the repercussion of medication nonadherence. The strategies to improve medication adherence were also identified. Conclusion This study provides clear evidence that the factors influencing medication adherence are multiple and interrelated. As the barriers of medication adherence are multiple, solutions/ interventions to improve adherence should be holistic, multifaceted, and patient-centered in order to be effective.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Medication adherenceMedication nonadherenceHeart failureBarriersFacilitatorsThesis or dissertation2023-10-01Recommended 6 month embargoThe full-text may be used and/or reproduced in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-profit purposes provided that: - A full bibliographic reference is made to the original source - A link is made to the metadata record in ChesterRep - The full-text is not changed in any way - The full-text must not be sold in any format or medium without the formal permission of the copyright holders. - For more information please email researchsupport.lis@chester.ac.uk