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Bi-exponential modelling of W' reconstitution kinetics in trained cyclists
Chorley, Alan Bott, Richard P. Marwood, Simon Lamb, Kevin L.
Chorley, Alan
Bott, Richard P.
Marwood, Simon
Lamb, Kevin L.
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2021-12-18
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Abstract
Purpose
The aim of this study was to investigate the individual W′ reconstitution kinetics of trained cyclists following repeated bouts of incremental ramp exercise, and to determine an optimal mathematical model to describe W′ reconstitution.
Methods
Ten trained cyclists (age 41 ± 10 years; mass 73.4 ± 9.9 kg; V˙O2max 58.6 ± 7.1 mL kg min−1) completed three incremental ramps (20 W min−1) to the limit of tolerance with varying recovery durations (15–360 s) on 5–9 occasions. W′ reconstitution was measured following the first and second recovery periods against which mono-exponential and bi-exponential models were compared with adjusted R2 and bias-corrected Akaike information criterion (AICc).
Results
A bi-exponential model outperformed the mono-exponential model of W′ reconstitution (AICc 30.2 versus 72.2), fitting group mean data well (adjR2 = 0.999) for the first recovery when optimised with parameters of fast component (FC) amplitude = 50.67%; slow component (SC) amplitude = 49.33%; time constant (τ)FC = 21.5 s; τSC = 388 s. Following the second recovery, W′ reconstitution reduced by 9.1 ± 7.3%, at 180 s and 8.2 ± 9.8% at 240 s resulting in an increase in the modelled τSC to 716 s with τFC unchanged. Individual bi-exponential models also fit well (adjR2 = 0.978 ± 0.017) with large individual parameter variations (FC amplitude 47.7 ± 17.8%; first recovery: (τ)FC = 22.0 ± 11.8 s; (τ)SC = 377 ± 100 s; second recovery: (τ)FC = 16.3.0 ± 6.6 s; (τ)SC = 549 ± 226 s).
Conclusions
W′ reconstitution kinetics were best described by a bi-exponential model consisting of distinct fast and slow phases. The amplitudes of the FC and SC remained unchanged with repeated bouts, with a slowing of W′ reconstitution confined to an increase in the time constant of the slow component.
Citation
Chorley, A., Bott, R., Marwood, S., & Lamb, K.L. (2022). Bi-exponential modelling of W′ reconstitution kinetics in trained cyclists. European Journal of Applied Physiology, 122, 677–689. https://doi.org/10.1007/s00421-021-04874-3
Publisher
Springer
Journal
European Journal of Applied Physiology
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DOI
10.1007/s00421-021-04874-3
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Article
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Description
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00421-021-04874-3
Series/Report no.
ISSN
1439-6319
EISSN
1439-6327