Lipid metabolism and hormonal interactions: Impact on cardiovascular disease and healthy aging
Mc Auley, Mark T. Mooney, Kathleen M.
Mc Auley, Mark T.
Mooney, Kathleen M.
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EPub Date
Publication Date
2014-05-31
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Abstract
Populations in developed nations are aging gradually; it is predicted that by 2050 almost a
quarter of the world’s population will be over 60 years old, more than twice the figure at the
turn of the 20th century. Although we are living longer, this does not mean the extra years
will be spent in good health. Cardiovascular diseases are the primary cause of ill health and
their prevalence increases with age. Traditionally, lipid biomarkers have been utilized to
stratify disease risk and predict the onset of cardiovascular events. However, recent evidence
suggests that hormonal interplay with lipid metabolism could have a significant role to play in
modulating cardiovascular disease risk. This review will explore recent findings which have
investigated the role hormones have on the dynamics of lipid metabolism. The aim is to offer
an insight into potential avenues for therapeutic intervention.
Citation
Mc Auley, M. T., & Mooney, K. M. (2014). Lipid metabolism and hormonal interactions: Impact on cardiovascular disease and healthy aging. Expert Review of Endocrinology & Metabolism, 9(4), 357-367. https://doi.org/10.1586/17446651.2014.921569
Publisher
Taylor & Francis
Journal
Expert Review of Endocrinology & Metabolism
Research Unit
DOI
10.1586/17446651.2014.921569
PubMed ID
PubMed Central ID
Type
Article
Language
en
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Series/Report no.
ISSN
1744-6651
EISSN
1744-8417