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Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells

Humphrey, Emma L.
; 
Williams, John H. H.
; 
Davie, Michael W. J.
; 
Marshall, Michael J.
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Affiliation
Robert Jones and Agnes Hunt Orthopaedic Hospital; University College Chester
EPub Date
Publication Date
2006-05
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Biological Sciences
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Abstract
This article demonstrates that dexamethasone, prednisolone, deflazacort and the dissociated glucocorticoids, RU24858, RU40066, RU24782, AL438-F1 and ZK216348 significantly inhibit osteoprotegerin (OPG) production in two human osteoblastic cell lines (MG63 and hFOB).
Citation
Humphrey, E. L., Williams, J. H. H., Davie, M. W. J., & Marshall, M. J. (2006). Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells. Bone, 38(5), 652-661. https://doi.org/10.1016/j.bone.2005.10.004
Publisher
Elsevier
Journal
Bone
Research Unit
URI
http://hdl.handle.net/10034/227131
DOI
10.1016/j.bone.2005.10.004
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PubMed Central ID
Type
Article
Language
en
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ISSN
8756-3282
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This article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies.
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http://www.journals.elsevier.com/bone/