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Phytochemical Analysis and In Vivo Antimalarial Activities of Ethyl Acetate Fraction of Spilanthes filicaulis on Mice Subjected to Plasmodium berghei
Ofeniforo, Bankole Emmanuel Ogunro, Olalekan Bukunmi Dike, Charles Ebere Agada, Samuel E. Akinwunmi, Kemi Feyisayo
Ofeniforo, Bankole Emmanuel
Ogunro, Olalekan Bukunmi
Dike, Charles Ebere
Agada, Samuel E.
Akinwunmi, Kemi Feyisayo
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2024-08-20
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Abstract
Malaria airs a life-threatening risk in Tropical African countries, stemming from infection by Plasmodium species. This region is richly endowed by nature with a wealth of diverse and largely unexplored plants that hold the potential for managing this protozoan parasite. The currently accessible over-the-counter drugs for disease management often present affordability challenges for the average person, exacerbated by the parasite’s increasing resistance to them. This study investigated the phytoconstituents present in the ethyl acetate fraction of Spilanthes filicaulis (EFSF) and explored the antimalarial effects of EFSF on mice infected with Plasmodium berghei.
Citation
Ofeniforo, B. E., Ogunro, O. B., Dike, C. E., Agada, E. S., & Akinwunmi, K. F. (2025). Phytochemical analysis and In Vivo Antimalarial activities of Ethyl Acetate Fraction of Spilanthes filicaulis on mice subjected to Plasmodium berghei. Vector-Borne and Zoonotic Diseases, 25(1), 26-33. https://doi.org/10.1089/vbz.2024.0039
Publisher
Mary Ann Liebert
Journal
Vector-Borne and Zoonotic Diseases
Research Unit
DOI
10.1089/vbz.2024.0039
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PubMed Central ID
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Article
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Series/Report no.
ISSN
1530-3667
EISSN
1557-7759
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