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High drug related mortality rates following prison release: Assessing the acceptance likelihood of a naltrexone injection and related concerns
Murphy, Philip N. Mohammed, Faizal Wareing, Michelle Cotton, Angela McNeil, John Irving, Paula Jones, Steven Sharples, Louisa Monk, Rebecca Elton, Peter
Murphy, Philip N.
Mohammed, Faizal
Wareing, Michelle
Cotton, Angela
McNeil, John
Irving, Paula
Jones, Steven
Sharples, Louisa
Monk, Rebecca
Elton, Peter
Advisors
Editors
Other Contributors
Affiliation
EPub Date
Publication Date
2018-07-04
Submitted Date
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Abstract
Background and aims. High drug related mortality amongst former prisoners in
the 4 weeks following release is an internationally recognised problem.
Naltrexone injections at release could diminish this by blockading opioid receptors,
but naltrexone is not licenced for injection for treating opiate misuse in the United
Kingdom and some other countries. This study examined the likelihood of
accepting a naltrexone injection at release, and the relationship of this likelihood
to other relevant variables.
Method. Sixty-one male prisoners with a history of heroin use, who were
approaching release from two prisons in the north-west of England, provided
likelihood ratings for accepting a naltrexone injection if it were to have been
available. Additional data was gathered regarding demographic and drug use
histories, and also from psychometric instruments relevant to drug misuse and
treatment preparedness.
Results. Maximum likelihood ratings for accepting a naltrexone injection were
recorded by 55.7% of the sample with only 9.8% indicating no likelihood of
accepting an injection. Likelihood ratings were positively related to serving a
current sentence for an acquisitive offence compared to drug related or violence
offences, and negatively related to peak methadone dosages during the current
sentence.
Conclusions. Although naltrexone injections were not available to participants in
this study, the findings suggest that the potential uptake for this intervention is
sufficient to warrant a clinical trial with this population of British prisoners, with a
view to potential changes to its current licencing status
Citation
Murphy, P., Mohammed, F., Wareing, M., Cotton, A., Mc Neil, J., Irving, P., Jones, S., Sharples, L., Monk, R. & Elton, P. (2018). High drug related mortality rates following prison release: Assessing the acceptance likelihood of a naltrexone injection and related concerns. Journal of Substance Abuse Treatment, 92, 91-98
Publisher
Elsevier
Journal
Journal of Substance Abuse Treatment
Research Unit
DOI
10.1016/j.jsat.2018.07.002
PubMed ID
PubMed Central ID
Type
Article
Language
en
Description
Series/Report no.
ISSN
0740-5472
EISSN
1873-6483