Publication

Homocysteine and cognitive decline in healthy elderly

McCaddon, Andrew
; 
Hudson, Peter R.
; 
Davies, Gareth K.
; 
Hughes, Alan
; 
Williams, John H. H.
; 
Wilkinson, Clare
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Affiliation
University of Wales College of Medicine; Wrexham Maelor Hospital; Royal Alexandra Hospital, Paisley; Chester College
EPub Date
Publication Date
2001-09
Submitted Date
Collections
Biological Sciences
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Abstract
Serum homocysteine is increased, and correlates inversely with cognitive scores, in Alzheimer's disease (AD), vascular dementia and "age-associated memory impairment". Elevated levels might signal accelerated cognitive decline, although this remains to be established. We therefore repeated Mini-Mental State Examinations, together with additional ADAS-Cog assessments, in 32 healthy elderly individuals to determine whether prior homocysteine levels predicted cognitive changes over a 5-year period.
Citation
McCaddon, A., Hudson, P. R., Davies, G. K., Hughes, A., Williams, J. H. H., & Wilkinson, C. (2001). Homocysteine and cognitive decline in healthy elderly. Dementia and Geriatric Cognitive Disorders, 12(5), 309-313. https://doi.org/10.1159/000051275
Publisher
Karger Publishers
Journal
Dementia and Geriatric Cognitive Disorders
Research Unit
URI
http://hdl.handle.net/10034/226331
DOI
10.1159/000051275
PubMed ID
PubMed Central ID
Type
Article
Language
en
Description
This article is not available through ChesterRep.
Series/Report no.
ISSN
1420-8008
EISSN
1421-9824
ISBN
ISMN
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This article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies.
Additional Links
https://karger.com/dem/article-abstract/12/5/309/97756/Homocysteine-and-Cognitive-Decline-in-Healthy?redirectedFrom=fulltext