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COVID-19 Presenting As Intussusception In Infants: a case report with literature review
Athamnah, Mohammad ; Masadeh, Salem ; Hamdallah, Hanady ; Banikhaled, Nasser ; Shatnawi, Wafa ; El Mughrabi, Marwa
Athamnah, Mohammad
Masadeh, Salem
Hamdallah, Hanady
Banikhaled, Nasser
Shatnawi, Wafa
El Mughrabi, Marwa
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EPub Date
Publication Date
2021-01-07
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Abstract
The novel Corona virus disease 2019 (COVID-19) first presented in Wuhan, China. The virus was able to spread throughout the world, causing a global health crisis. The virus spread widely in Jordan after a wedding party held in northern Jordan. In most
cases of COVID-19 infection, respiratory symptoms are predominant. However, in rare cases the disease may present with non-respiratory symptoms. The presentation of COVID-19 as a case of intussusception in children is a strange and rare phenomenon.
We present here a case of a two-and-a-half month old male baby who was brought to hospital due to fever, frequent vomiting, dehydration and blood in stool. He was diagnosed as intussusception. The child was tested for corona due to the large societal
spread of the virus and because he was near his mother, who was suffering from symptoms similar to corona or seasonal flu (she did not conduct a corona test). Patient was treated without surgery and recovered quickly. The COVID-19 infection was
without respiratory symptoms, and there was no need for the child to remain in hospital after treatment of intussusception. The relationship between viruses, mesenteric lymphoid hyperplasia, and intussusception is a confirmed relation. ACE2 is the key
receptor required for SARA-COV-2 to enter the host cells. ACE2 has been also found in the brush border of the intestinal mucosa, as well as it is a key inflammatory regulator in the intestine. This may suggest that SARSA-COV-2 could invade the respiratory tract as well as gastrointestinal tract or both. Few case reports documented the presentation of COVID-19 as intussusception in children. In the light of the widespread of corona virus, performing COVID-19 tests for children with intussusception
can help linking the two entities. Development of gastrointestinal symptoms in COVID19 positive children should raise concern about the development of intussusception.
Citation
Athamnah, M. N., Masade, S., Hamdallah, H., Banikhaled, N., Shatnawi, W., Elmughrabi, M., & Al Azzam, H. S. (2021). COVID-19 presenting as intussusception in infants: A case report with literature review. Journal of Pediatric Surgery Case Reports, 66, 101779. https://doi.org/10.1016/j.epsc.2021.101779
Publisher
Elsevier
Journal
Journal of Pediatric Surgery Case Reports
Research Unit
DOI
10.1016/j.epsc.2021.101779
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PubMed Central ID
Type
Article
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EISSN
2213-5766
